Orthotics work in mysterious ways

We Move in Mysterious Ways

The Mysterious Ways of ErbB2/HER2 Trafficking

The EGFR- or ErbB-family of receptor tyrosine kinases consists of EGFR/ErbB1, ErbB2/HER2, ErbB3/HER3 and ErbB4/HER4. Receptor activation and downstream signaling are generally initiated upon ligand-induced receptor homo- or heterodimerization at the plasma membrane, and endocytosis and intracellular membrane transport are crucial for regulation of the signaling outcome. Among the receptors, Erb...

Anaesthetists understand their work in different ways.

Editor—We read with interest the investigation by Larsson and colleagues 1 reporting their qualitative study of how trainee anaesthetists understand their work. We congratulate them on their decision to pursue this type of enquiry. Only by addressing those aspects of anaesthetic expertise, which cannot be set out in syllabuses and measured as competencies, can a true picture of the complexity o...

Orthotics in neurorehabilitation.

II. Orthotics